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Cannabis can lower a person's potential to suppose or think clearly. It is usually given as the unit of an individual's power intake for energy (and alcohol for vitality) and is generally referred to as the energy density per litre. These considerations arise, partly, from proof that publicity of experimental animals to acute, high doses of amphetamine or methamphetamine produces damage, generally referred to as “neurotoxicity”, to dopaminergic neurons innervating the dorsal striatum (caudate-putamen). Nuclear medication procedures have indicated that availability of the dopamine transporter within the striatum decline at a fee of 6 − 7% per decade 61-63, and measures of nigrostriatal neurons have indicated a loss of 70% in the putamen after the age of fifty five years 64. As well as, the age-related lack of dopamine seems to accelerate after age 60 63, 64. 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