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Lisdexamfetamine is a substituted amphetamine with an amide linkage formed by the condensation of dextroamphetamine with the carboxylate group of the essential amino acid L-lysine. One review highlighted a nine-month randomized controlled trial of amphetamine therapy for ADHD in children that found an average increase of 4.5 IQ points, continued increases in consideration, and continued decreases in disruptive behaviors and hyperactivity. Stimulants like Vyvanse are the most effective therapy for ADHD for most children. The lisdexamfetamine in Vyvanse is converted into dextroamphetamine by the body. 98%) converted to its energetic metabolite D-amphetamine within the circulation (Pennick, 2010; Sharman and Pennick, 2014). 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