Mesothelioma Treatment OptionsPatients with mesothelioma should consult an expert for the best treatment option. Many specialists offer new and innovative therapies that can improve prognoses and symptoms.Mesothelioma can be treated by doctors through surgery, chemotherapy, and radiation therapy. Certain types of mesothelioma might also respond to immunotherapy drugs. Mesothelioma can recur after treatment. Doctors can prevent it from happening again by causing the pleura to stick to each other (pleurodesis) or draining fluid with the chest tube (peritoneal Mesothelioma). The best treatment plans incorporate these strategies.SurgeryMesothelioma treatment options are based on the type of mesothelioma a patient is diagnosed with along with the stage and other aspects like age. The doctor will determine the best mesothelioma treatment for you during the initial assessment.The surgeon will perform surgery to remove the largest mesothelioma that is possible. The surgeon can also perform other treatments either during or following the surgery. Mesothelioma treatments can include chemotherapy and radiation. Targeted therapy, immunotherapy and palliative procedures can manage symptoms and improve the quality of life for patients.People with pleural mesothelioma undergo a radical surgical procedure called extrapleural pneumonectomy (EPP) to eliminate the tumor and a large portion of the affected lung, in addition to the lung's lining (pleura) and a portion of the diaphragm as well as the sac surrounding the heart (pericardium). Another surgery that can be performed is pleurectomy/decortication (P/D). This procedure removes the pleura away, but leaves the affected lung in place. P/D is less invasive than EPP and has had some success in extending survival times. Some cancer centers provide heated intraoperative chemotherapy to kill cancer cells after surgery.During the procedure patients are put under anesthesia and given medicines to aid in sleeping or feeling no pain. During this period the medical team will collect vital information about your health such as your heart rate and blood pressure.After surgery the patient will receive chemotherapy and/or radiotherapy. Chemotherapy is a method to stop mesothelioma's growth and to kill any cells that remain after surgery. Different types of chemotherapy are used to treat mesothelioma, such as doxorubicin (Adriamycin), cyclophosphamide and pemetrexed. Most often, these drugs are administered via IV.Radiation is an extremely efficient treatment for mesothelioma since it utilizes high-energy beams to kill cancerous cells. Radiation can be administered on its own or in combination with other treatments. It is a treatment option for all types of mesothelioma, but it is likely to be beneficial in cases involving mesothelioma that is pericardial or peritoneal.Recurrent tumors can be seen in people who have mesothelioma regardless of treatment. Recurrent mesothelioma can occur in the same location as it did before or be spread to other organs, like the liver or brain. Certain patients with recurrent mesothelioma might require additional treatments, such as targeted therapy or immunotherapy, which may improve survival and reduce the risk of the cancer returning.ChemotherapyChemotherapy is among the most powerful treatments for mesothelioma. It involves injecting patients with medications that destroy cancer cells and prevent their growth or spreading. Mesothelioma doctors may use chemo on its own, or in conjunction with other treatment options, such as radiation therapy or immunotherapy.The kind of cancer and the stage of the cancer will determine the appropriate chemotherapy regimen for patients. Doctors are able to prescribe a variety of chemotherapy drugs, however pemetrexed and cisplatin are most common. Pemetrexed kills mesothelioma tumours by targeting cells that make the proteins cancer cells require to expand. Cisplatin is an anticancer drug which binds to the DNA of mesothelioma cells and causes them to die. The drugs can be administered intravenously or via mouth.Doctors can administer intraoperative chemotherapy during a mesothelioma operation. The chemotherapy drugs are heated and released into the chest cavity or abdominal cavity while the surgeon is still performing. This treatment is used to eliminate any microscopic tumors that the surgeon can't detect after surgery.Mesothelioma patients may also receive adjuvant chemotherapy after their surgeries. However, a majority of doctors wait until there is mesothelioma that has recurred before using this option. mesothelioma advanced treatment is because mesothelioma treatment procedures can be so invasive that a patient may not be healthy enough to undergo chemotherapy immediately after the operation.If mesothelioma is found to be back, the treatment will be focused on preventing the cancer and relieving symptoms. Some patients will do everything to eliminate their cancer, whereas others might prefer to manage it and live as pain-free as they can. It is essential that a patient with recurrent mesothelioma discuss the situation with their doctor and weigh the pros and cons. A patient may also want to enroll in a clinical study of mesothelioma treatments that are new. These trials can test a new combination of conventional treatments or a completely new treatment method for mesothelioma. Certain studies have demonstrated for instance, that immunotherapy is a successful treatment for recurrent mesothelioma.Radiation TherapyRadiation therapy involves the use of high-energy radiation and particles to destroy cancerous cells. The doctors treating mesothelioma typically recommend radiation therapy following surgery or in combination with other treatments. It can also be used as a symptom-relieving treatment for symptoms such as breathlessness or pain. The newest kinds of radiation have better control, making it easier to target tumors and avoid nearby healthy tissue.Treatment options will be based on the type of mesothelioma that you have and where it is located. You can also discuss experimental treatments with your physician like immunotherapy. Clinical trials are research studies that test the safety and effectiveness of new medications or procedures. These trials are conducted with patients who have volunteered to participate.A mesothelioma expert can help you find the right clinical trial for you.Surgery can reduce tumor size and reduce symptoms. Mesothelioma cannot be cured by surgery. It is possible that the cancer will come back or spread to other parts of the body. The majority of patients with mesothelioma are treated with various therapies.For pleural mesothelioma, surgical options include pleurectomy/decortication (P/D) and extrapleural pneumonectomy (EPP). The pleura is removed during P/D. This thin membrane that is a part of the lungs, chest wall and lining of the pleura. It can also eliminate any visible tumors that are present on the lung or chest wall. EPP is a more extensive procedure that is used to treat mesothelioma that is in its advanced stages. This procedure involves the removal of the entire lung along with the diaphragm, pleura and any visible tumors on the chest wall.Radiation may be used after pleural mesothelioma operation to kill any microscopic cancerous areas that were not removed during the procedure. This is referred to as adjuvant mesothelioma radiation. It is also used to relieve symptoms such as chest discomfort, breathing difficulties, or difficulties swallowing in peritoneal cancer patients before a procedure referred to as cytoreduction using heated chemotherapy (HIPEC).Radiation can cause long-term effects. The most frequent adverse effects are the skin's changes and fatigue. In rare cases it may cause long-term damage to the lungs and can cause persistent breathing problems or a narrowing of the esophagus. You should discuss these risks with your physician prior to deciding on radiation.ImmunotherapyCancer is caused by genetic mutations that cause abnormal cells to grow uncontrollably. As the cells multiply, they create tumors that infiltrate and destroy healthy tissue. Over time, tumors can spread throughout the body causing symptoms such as fatigue, pain, and difficulty breathing. The mesothelium is a protective covering around the organs that protects them from lung cancers caused by asbestos.Doctors diagnose mesothelioma through a physical examination and taking a detailed record regarding your asbestos exposure. They will also conduct medical tests including blood work and various kinds of scans. These scans offer a high-resolution view of your body and may reveal signs of mesothelioma such as lung fluid, or cancerous tumors. X-rays are the most commonly used imaging test used to identify mesothelioma. However doctors will often require more advanced scans such as CT, PET and MRI. In addition, doctors may perform a biopsy to confirm the mesothelioma diagnosis and to ensure that the cancer is not spreading.Mesothelioma is not curable by doctors in most patients, but can manage the disease through chemotherapy and other treatments. The aim is to eliminate the most mesothelioma possible and to reduce the likelihood that cancer will return.For mesothelioma that is advanced doctors may perform a procedure to help prevent the buildup of fluid inside the lung (pleurodesis), or they might place a tube in the chest to allow regular draining of excess liquid (pleural effusion drainage). They can also attempt to stop the growth of tumors by creating the outer layer of the lung connect to the inner layer of the lungs. (extrapleural pneumonectomy) or by shrinking them with radiation therapy.Immunotherapy is a brand new treatment that uses medications to stimulate your immune system to fight the cancer. The U.S. Food and Drug Administration has approved these medications including Keytruda and Opdivo to be used in clinical trials of mesothelioma. This treatment is promising and could result in better outcomes in certain patients. Immunotherapy can trigger side effects such as fatigue chills, fever, and fatigue. However, these are less severe than more aggressive treatments.