Union Pacific Cancer ClusterThe Union Pacific Rail Yard, northeast of Houston is contaminated by one chemical that is linked to a cancer cluster. These chemicals include dioxin and creosote.A study found that a significant amount of contaminants dissolved into ground water and the soil surrounding the railyard. Researchers believe that residents who have been affected have been diagnosed with a range of illnesses including skin cancer, prostate tumors and bile duct cancer that is a form of liver cancer.CreosoteCreosote is an organic compound that contains hundreds of chemicals that are used to preserve wood and other materials. It is suspected to be a carcinogen. Creosote is known to cause eye damage and skin irritation, as well as cancer.The union Pacific cancer cluster is a group of neighborhoods in Houston which are contaminated with creosote waste. Union Pacific has been protesting the pollution for months , and the community is demanding that they eliminate it.It has been a long and difficult battle for residents to get the company to clean up the pollution. But they haven't given up and are seeking to sue the railroad company in federal court, hoping that the company will take responsibility for the contamination.They claim that creosote an endocrine-depleting substance, is damaging their homes and causing people sick. They say that pollution causes cancer in children five times more than the national average.In Cancer Lawsuits to causing illness In addition, the pollution is leading residents to lose their jobs and their homes. The contamination is getting into the soil as well as the air, water, and soil of the area.According to the Houston Chronicle, creosote was eliminated from the site which was owned by Southern Pacific, for decades before it was acquired by Union Pacific in 1997. The company did not take responsibility for the pollution until recently, when residents initiated an effort to eliminate the polluted area.Despite their efforts, residents of the union pacific cancer cluster continue suffer from ailments such as Esophagus and lung cancers. They also have high rates of childhood lymphoblastic leukemia.While researchers do not know the exact cause of the contamination, they believe that it is caused by the chemicals in creosote. These chemicals are linked to increased risks of lung, esophagus and throat cancers.The chemical is said to be employed in a variety of ways, including preservation of wood and as a cure for the ringworm. It is also used in insecticides and fungicides.Research has demonstrated that creosote chemicals undergo an oxidation reduction process that makes them toxic. This process can lead to biodegradation, which results in and release toxic byproducts in the soil and water. Railroad Workers can take some time, and it is only possible if the initial chemical compound is not low enough.DioxinDioxin is one of the chemicals that have been linked to many types of cancers. It is toxic to kidneys, livers and central nervous system.The chemical is present in the air, soil and water. It can also be absorbed by the skin, or eaten in food. It is part of the so-called "dirty dozen" chemicals.People who are exposed at high levels of dioxins due to workplace exposure or industrial accidents might be suffering from health issues including liver issues and thyroid disease. However, the effects on health of dioxins with low levels are not known.The long-term effects of this contaminant remain being studied by scientists. It has been linked with cancer in laboratory animals and people who live in areas.According to the World Health Organization (WHO), dioxins have been proven to increase the risk of certain kinds of cancer. They can also damage the reproductive and immune systems. They can also cause birth defects.Dioxins are absorbed by different ways, including eating foods high in fat and burning household waste and exposure to hazardous materials. Industrial accidents, pesticides, and herbicides are also sources of dioxins in our environment.If you smoke, you are more likely to have higher levels of dioxins than the other people. It is possible to reduce your risk by stopping smoking.Healthy, balanced, nutritious diets are crucial, particularly when it comes to fruits, vegetables as well as grains and other food items. They can to reduce or eliminate your exposure to dioxins and their compounds.A healthy diet can protect you from other health problems caused by dioxins, such as lung or bronchus cancers. In addition, you should avoid eating meat and milk products with high levels of fat.Selecting foods that are low in fat can help to reduce your exposure to dioxins. It is also essential to eat lots of fresh fruits as well as vegetables and drink plenty of water.Dioxin is a dangerous chemical, has been linked to various types of cancers, including breast and liver cancer. It can cause damage to the heart, brain, and lungs.Toxic MetalsMetals like cadmium and copper are essential for our lives, but can become harmful if used in too large. They are also found at tiny levels in sewage, and other polluting sources as well as in certain electronic waste (e-waste).A number of heavy metals in the environment are associated with various diseases, including cancer. Despite their significance in the development and onset of these conditions however, it isn't known how they impact different organ systems.The toxicity of heavy metals is based on the chemical properties of individual ions and the specific cells that they bind to. These interactions include the production of ROS, inhibition enzymes that produce compounds that are oxidative and inactivation of other proteins that protect cells from toxic effects.Each metal is distinct in the degree of toxicity it can cause. For instance, cadmium or copper can weaken antioxidant defense by producing superoxide anion radicals (ROS) which damage mitochondrial DNA and mitochondrial function. In addition that these metals are able to attach to protein phosphatases (PP) and inactivate glutathione peroxidase.Lead, arsenic and other oxidative stresses that can cause inflammation or lipid peroxidation are often linked to these. These oxidative stressors can lead to heart disease, lung cancer and other health problems.This is especially relevant to arsenic and lead which may trigger pro-inflammatory chemokines, which promote cancer cell growth. It is also possible that these chemicals interact with genes involved in the regulation of cell cycle progression as well as DNA repair to enhance their mutagenic and carcinogenic effects.The risk of developing prostate cancer is just one of the many roles that heavy metals play. This is of great concern since prostate cancer is the most prevalent form of cancer that men suffer from and the leading cause of death due to the disease in the United States.In addition, copper and cadmium have been found to increase the risk of developing cardiovascular health as well as coronary heart disease and stroke. These findings are of particular significance because they provide evidence for the (often not widely recognized) importance of toxic metals found in the environment in increasing risk of cardiovascular disease beyond their role as behavioural factors. However further research is required to better understand the relationships and determine the causality.PesticidesPesticides are substances that are used to control weeds, insects and fungi as well as other agricultural pests (Langley and Mort 2012; Mostafalou and Abdollahi 2017). They are essential to maintain the production of agricultural products and provide safe food for people. However, they can be harmful to the environment and to human health when absorbed through direct contact with skin or by inhalation.In the United States, the number of pesticides that are used is estimated at more than 1.1 billion pounds per year. This is a lot of harmful chemicals that could either be inhaled or ingested. The Environmental Protection Agency regulates pesticide use.Although pesticides are commonly applied on a variety of crops, there is growing concern about their impact on human health as well as the environment. Certain pesticides have been classified by the World Health Organization as potentially carcinogenic or may cause cancer.This has led to an increase in the number of research efforts to examine the link between exposure to pesticides and health outcomes such as cancer. These studies use various methods such as multilevel mixed effect models as well as Cox proportional risk regressions.These methods are commonly used to evaluate the relationship between a specific chemical and health outcomes like cancer at a local, state or national level. This analysis is especially important as it gives a broad overview of the possible connections between environmental agents, health outcomes, and also allows for targeted research on specific chemicals. Railroad Workers of pesticides is their potential exposure through occupational activities that involve the application, transportation, and storage. This kind of exposure could be influenced by a variety of factors, including the location of the worker as well as the type of products employees use.Pesticides can also be absorbed through the skin, or via inhalation. They could also be present as food. This could be harmful to human health, especially for infants and children.Pesticides also contaminate the air and groundwater and can cause kidney damage and respiratory issues. The pollutants can be released through a variety sources, such as factories and waste incinerators. Dioxins are among the most hazardous in that they can lead to cancer, as well as other diseases like liver disease.