Union Pacific Cancer ClusterThe Union Pacific Rail Yard just northeast of downtown Houston is contaminated by chemicals that are connected to a cancer cluster. The chemicals include creosote as well as dioxin.A study has revealed that groundwater and soil around the railyard were contaminated with significant amounts of toxins. Researchers have discovered that residents affected are diagnosed with skin, prostate and cancers of the bile duct. This is a type liver cancer.CreosoteCreosote, a mixture of hundreds of chemicals used to preserve wood and other materials, is a probable carcinogen. In addition to cancer, creosote also known to cause eye damage and dermatitis.Houston's union pacific cancer cluster is comprised of an area that is infected by creosote. Railroad Cancer Settlements has been protesting against the pollution in recent months, and is demanding that Union Pacific remove the waste.Residents have fought for decades to force the company to take care of their pollution. They are not giving up, and are currently suing the railroad company in federal courts, hoping the company will finally acknowledge responsibility for the contamination.They claim that creosote an endocrine-depleting substance, has been creating a toxic environment in their homes, and has made them sick. They claim that the pollution causes children to develop cancer at five times the rate of national average.In addition to the health effects and causing environmental pollution, it is leading residents to lose their jobs and their homes. The pollution is leaking into the soil as well as the air and water of the neighborhood.According to the Houston Chronicle creosote was removed from the site by Southern Pacific for many decades before it was bought by Union Pacific in 1997. The company did not take responsibility for the contamination until recent residents started a movement.Despite their efforts, residents in the union pacific cluster continue to suffer from esophageal and lung cancers. They also have high levels of childhood lymphoblastic leukemia.While researchers don't know the exact cause of the contamination, they believe that it is due to chemicals in creosote. These chemicals are linked to increased risks of lung, esophagus and throat cancers.It is believed that the chemical was used in a variety of ways that included wood preservation as well as an anti-ringworm treatment. It is also used in fungicides, insecticides, and other fungicides.Research has demonstrated that creosote chemical compounds undergo an oxidation-reduction process which renders them harmful. This can lead to the biodegradation and release of toxic byproducts into soil and water. However, the process could take time and can only be effective if the initial chemical compounds are low enough in concentration.DioxinDioxin is among the chemicals that has been linked to various types of cancers. It is harmful to kidneys, livers and central nervous system.The chemical is present in the soil, air and water. It can be absorbed through the skin or swallowed by eating. It is part of the so-called "dirty dozen" chemicals.People who are exposed at high levels of dioxins through occupational exposure or industrial accidents could develop health issues including liver problems , and thyroid diseases. However, the health consequences of low levels dioxins are not known.Researchers are still investigating the long-term effects of the contaminant. It has been linked to cancers in laboratory animals as well as in people who live near contaminated areas.According to the World Health Organization (WHO), dioxins have been shown to increase the risk of certain types of cancer. They also may harm the immune system and reproductive systems. In addition, they can cause some kinds of birth defects.Dioxins can be absorbed in numerous ways, including eating foods high in fat as well as burning household waste and exposure to dangerous substances. Industrial accidents, pesticides, and herbicides are all sources of dioxins found in our environment.You are more likely to experience more levels than others smoking cigarettes. You can reduce the risk by quitting smoking.It is also essential to eat healthy, nutritious and balanced meals, particularly vegetables, fruits and grains. These foods can help reduce or limit your exposure to dioxins as well as their compounds.A healthy diet can also help you to avoid other health issues caused by dioxins, such as lung cancer or bronchus cancers. In addition, you should avoid eating meat or dairy products that contain high levels of fat.You can limit your exposure by selecting foods that are low in fat. Railroad Cancer Lawsuit Settlements is also important to eat plenty of fresh fruit and vegetables , and drink lots of water.Dioxin, a hazardous chemical has been linked with various types of cancers, including breast and liver cancer. It can be harmful to the heart, brain and lung tissue.Toxic MetalsMetals like copper and cadmium are vital to our lives, but can be toxic if they are too high. They can also be found in small amounts in sewage and other pollutants as well as in certain electronic waste (e-waste).Many environmental heavy metals have been linked with a variety of diseases, including cancer. Despite their significance in the development and onset of these conditions, it is still not evident how they affect various organ systems or how to avoid their toxicity.The toxicity of heavy metals varies on the chemical properties of the individual ions as well as the specific cells that these ions bind to. These interactions include the production of ROS, inhibition of enzymes that make oxygen-producing metabolites and the inactivation other proteins that could be able to protect cells from toxic.Alongside these common mechanisms, every metal has its own distinctive toxicity. Copper and cadmium for instance, may weaken antioxidant defenses , causing superoxide anionradios (ROS), which damage mitochondrial functions and DNA. In addition they can attach to protein phosphatases (PP) and cause glutathione to be inactivated peroxidase.Lead, arsenic and other oxidative stressors that trigger inflammation or lipid peroxidation are also often associated with these. These oxidative stressors can cause lung cancer, heart disease and other health problems.This is especially the case for lead and arsenic, which can activate the expression of pro-inflammatory chemokines and microRNAs, which promote the growth of cancer cells. It is possible that these chemicals interplay with genes involved in cell cycle progression and DNA repair to enhance their mutagenic or carcinogenic properties.Another important function of heavy metals is the fact that they can increase the risk of prostate cancer. This is a significant concern since prostate cancer is the most common form of cancer among men and the leading cause of death in the United States.In addition, copper and cadmium have been shown to increase the risk of coronary heart disease, coronary heart disease and stroke. These findings are significant because they demonstrate the (often under-recognised) importance of environmental toxic metals in enhancing cardiovascular risk beyond their roles as behavioural predictors. However there is a need for more research to better understand the connections and to determine causality.PesticidesPesticides are substances that are used to control weeds, insects and fungi as well as other agricultural pests (Langley and Mort 2012; Mostafalou and Abdollahi 2017). They are vital in maintaining agricultural production and provide safe food for the population. They can cause harm to the environment and human health if they are inhaled or come into direct contact with skin.In the United States, the number of pesticides used is estimated to be more than 1.1 billion pounds annually. This is a large amount of toxic chemicals that can be inhaled, or ingestion. The Environmental Protection Agency regulates pesticide use.While pesticides are often used on different crops, there is increasing concern about their effects on human health and the environment. Certain pesticides are classified by the World Health Organization as potentially carcinogenic or can cause cancer.There is a growing effort to study the connection between exposure to pesticides and cancer. These studies employ a variety of methods such as multilevel mixed effect models as well as Cox proportional risks regressions.These methods are often utilized to determine the connection between a single chemical and health outcomes like cancer at the state, regional or national scale. This is especially important since it provides a comprehensive overview of the possible connections between environmental pollutants and health outcomes, which allows to conduct focused research on specific chemicals.Another major impact of pesticides on human health is the potential for exposure through occupational activities that involve the use transportation, storage and transportation of these substances. Railroad Cancer Lawsuit Settlements of exposure can be influenced by a variety of factors, such as the location of the worker and the type of products workers use.Pesticides can also be absorbed through the skin or inhalation. They may also be present in food. This could be harmful to health, especially for infants and children.Pesticides, in addition, can pollute the air and groundwater, which can lead to respiratory disorders and kidney damage. These pollutants are released from a variety of sources, including factories and waste incinerators. The most dangerous are dioxins, which can cause cancer and other illnesses such as liver disease.