Union Pacific Cancer ClusterThe Union Pacific Rail Yard just northeast of downtown Houston is contaminated with chemicals that are linked to a cancer cluster. The chemicals include creosote and dioxin.A study has revealed that a significant amount of the toxins seeped into ground water and the soil surrounding the railyard. Researchers have found that residents affected have been diagnosed with a variety of diseases including prostate cancer, skin cancer tumors and bile duct cancer that is a form of liver cancer.CreosoteCreosote, a compound, contains hundreds of chemicals that are used to preserve wood and other materials. It is suspected to be carcinogen. In addition to cancer, creosote is also known to cause eye damage and dermatitis.The union Pacific cancer cluster is a collection of neighborhoods in Houston that are contaminated with creosote waste. Union Pacific has been protesting the contamination for months and the community is demanding that they get rid of it. Railroad Cancer Lawsuit have fought for many years to get the company to remove their pollution. They haven't given up, and are now suing the railroad company in federal courts, hoping that the company will finally acknowledge responsibility for the contamination.They say that creosote is an endocrine-depleting substance that has been contaminating their homes and causing them to become ill. They claim that the pollution is causing children to develop cancer at five times the national average.The pollution is causing illness and is threatening the lives of residents. The pollution is leaking into the soil, water and air in the neighborhood.According to the Houston Chronicle creosote was removed from the site by Southern Pacific for many decades before it was bought by Union Pacific in 1997. The company didn't take responsibility for the pollution until the last few years, when residents began an effort to clean up the polluted area.Despite their efforts, residents in the union pacific region continue to suffer from lung and esophageal cancers. They also have high levels of childhood lymphoblastic leukemia.While scientists aren't able to pinpoint the exact cause of the contamination, they believe that it is caused by chemicals in creosote. These chemicals have been linked with an increased risk of developing throat, esophus, and lung cancers.It is believed that the chemical was used in a variety ways, including wood preservation and as an anti-ringworm treatment. It is also a frequent ingredient in insecticides and fungicides.Research has proven that creosote compounds have an oxidation-reduction procedure that renders them harmful. This process can lead to biodegradation of these compounds, which releases toxic byproducts into soil and water. However, this process can take time and can only be efficient if the chemical compounds are low enough in concentration.DioxinDioxin is just one of the chemicals that have been linked to different types of cancers. It is harmful to kidneys, livers and the central nervous system.The chemical is found in the soil, air, and water. It can be absorbed through the skin or swallowed by eating. It is a part of the so-called "dirty dozen" chemicals.Dioxins in high concentrations can cause health problems like liver and cancer when people are exposed to them in industrial accidents or occupational exposure. However, the effects on health of dioxin exposure at low levels are not clear.Researchers are still researching the long-term effects the contaminants. It has been linked to cancers in lab animals , as well as people who live near contaminated areas.According to the World Health Organization (WHO) dioxins have been found to increase the risk of certain types of cancer. They also can harm the immune and reproductive systems. They can also cause birth defects.Some of the most common ways that dioxins are absorbed include eating fatty foods as well as burning household waste and being exposed to hazardous waste. Other sources of dioxins that are found in the environment include industrial accidents, herbicides and pesticides.You are more likely to have more levels than others smoking cigarettes. You can lower your risk by stopping smoking.Healthy, balanced and nutritious diets are important, especially when it concerns vegetables, fruits grains, grains, and other food items. These can help prevent or limit the exposure to dioxins and their compounds.Healthy eating habits can help you avoid other health problems such as lung cancers or bronchus. In addition, you should be wary of eating meat and dairy products that contain high levels of fat.You can reduce your exposure by choosing foods that are lower in fat. It is important to consume lots of fresh vegetables and fruits, and to drink plenty of water.Dioxin is a dangerous chemical that has been linked to many types of cancers, including breast cancer and liver cancer. It can be harmful to the heart, brain and lung tissue.Toxic MetalsMetals like copper and cadmium are vital to our lives, but they can become toxic if they are used up too excessively. They can also be found in tiny amounts in sewage, and other polluting sources as well in electronic waste (ewaste).A number of heavy metals from the environment have been linked with many different diseases, including cancer. Despite their importance in the development and onset of these conditions it isn't clear which organ systems.The toxicity of heavy metals is dependent on the chemical properties of the individual ions and the cellular target that these ions bind to. These interactions include the formation of ROS, inhibition of enzymes that generate the oxidative metabolites, and the inactivation of other proteins that are able to protect cells against toxicity.In addition to these common mechanisms, each metal has its own distinct toxicity. Cadmium and copper for instance, can weaken antioxidant defenses through the generation of superoxide anionradios (ROS) which can damage mitochondrial and DNA functions. In addition they can connect to protein phosphatases (PP) and block glutathione peroxidase.In the same way, arsenic as well as lead are often linked to the oxidative stress that results in inflammation and lipid peroxidation. These oxidative stressors can lead to lung cancer, heart disease and other health issues.This is particularly relevant to arsenic and lead that can trigger pro-inflammatory chemokines, which promote cancer cell growth. It is possible that these chemicals may interplay with genes involved in cell cycle progression and DNA repair to increase their mutagenic and carcinogenic effects.Another significant role played by heavy metals is the fact that they can increase the risk of developing prostate cancer. This is an important issue since prostate cancer is among the most common type of cancer for men and the leading cause of deaths in the United States.Copper and cadmium also increase the risk of developing stroke, coronary heart disease, and cardiovascular disease. These findings are significant as they show the importance of toxic metals that are found in the environment in increasing cardiovascular risk. They also play an important role as behavioral factors. However, more research is needed to better identify the connections and determine causality.PesticidesPesticides are chemical compounds that are used to control pests and diseases as well as fungi in the field of agriculture (Langley and Mort 2012, Mostafalou and Abdollahi 2017,). They are crucial to maintain agricultural production and providing food products that are safe for humans. However, they can also be harmful to the environment and health of humans when they come into direct contact with skin or by inhalation.In the United States, the number of pesticides being used is estimated to be more than 1.1 billion pounds annually. This is an enormous amount of toxic chemicals which can be inhaled or ingested. The use of pesticides is controlled by the Environmental Protection Agency.Pesticides are commonly used on many crops. However, there is increasing concern about their effects on the environment as well as human health. The World Health Organization has classified certain pesticides as potentially carcinogenic or cancer-causing.There is a growing effort to determine the relationship between exposure to pesticides and the development of cancer. These studies use diverse methods which include multilevel mixed effects models as well as Cox proportional risks regressions.These techniques are commonly used to analyze the relationship between a specific chemical and health effects like cancer, at a state, regional or national level. This analysis is especially important since it provides a broad overview of the possible connections between environmental agents, health outcomes, and also allows for targeted research on specific chemicals.Another major impact of pesticides on health is the potential for exposure through work-related activities that require the application or transportation of these substances. This is influenced by a variety of aspects, including the location of the worker as well as the chemicals they use.Pesticides are also absorbed through the skin, or via inhalation. They could also be present as food. This can cause harm to the health of children and infants.Pesticides also contaminate the air and groundwater which can cause respiratory disorders and kidney damage. These pollutants are released by a variety of sources, including factories and waste incinerators. Dioxins are among the most harmful because they can cause cancer and other diseases like liver disease.