Abdominal Mesothelioma TreatmentResearchers and doctors are working together to improve the treatment for mesothelioma. The most commonly used treatment options include radiation, surgery and chemotherapy.Doctors diagnose peritoneal asbestosis with physical examination and tissue sample. A surgeon inserts a needle under the skin of the abdomen or chest and collects fluid or tissue for testing.CytoreductionCytoreduction is the most efficient treatment for patients suffering from peritoneal Msothelioma. In this procedure, doctors eliminate the abdominal lining cavity, as well as any visible cancerous tissue or tumors. Doctors perform this procedure through an incision in the belly button, or by making small incisions on the abdomen. The procedure can last up to 12 hours. It is often paired with HIPEC, which involves heated chemotherapy drugs being pumped through the abdominal cavity after surgery.HIPEC is a mesothelioma treatment that is only available in specialized centers. It can dramatically improve the prognosis of a patient. It is not recommended for all mesothelioma patients especially those with advanced cancer.Specialists in mesothelioma use medical exams to determine whether a patient is able to. They will use a CT scan and biopsy results to determine how far the mesothelioma spread throughout the body. Then, they will determine if the patient qualifies for HIPEC cytoreduction.Doctors may also incorporate systemic chemotherapy into the surgical plan. This is usually performed prior to cytoreductive surgery or within the first month following the operation. After this type of treatment for mesothelioma, patients should not return to their jobs for at least six weeks.Doctors may require combining five surgical procedures during the process of cytoreduction to completely eliminate mesothelioma cancer cells. They'll also have to remove any mesothelioma cell and fluid. In order to reach the peritoneal area, doctors will perform a laparotomy or open abdominal surgery. It is also possible to use another procedure, such as a colectomy or bowel resection.A study published in the Journal of Gastrointestinal Surgery revealed that delaying mesothelioma surgery and HIPEC can result in a lower long-term survival rate. The researchers recommend that patients with peritoneal mesothelioma receive immediate referral to a clinic which offers this treatment. In new mesothelioma treatment , the authors suggest that health insurance companies provide coverage for this surgery for mesothelioma patients. In some instances veterans can receive this treatment via VA benefits.Hyperthermic intraperitoneal chemotherapy (HIPEC)As a component of cytoreduction surgery, HIPEC involves bathing the abdominal cavity with heated chemotherapy to eliminate any cancerous cells left after surgery. In this procedure surgeons insert catheters in the abdomen and connect them to an infusion pump that circulates the drug solution to and from the patient's body. The process can last anywhere between 30 minutes and 120 minutes. During the treatment, doctors will move the patient's body back and forth to ensure that the medication is absorbed into all areas of the abdominal cavity. Following the chemotherapy, the doctors drain the fluid out of the body, and stitch the surgical wound, and then transfer the patient to a hospital for intensive medical attention.Doctors usually use a mix of chemotherapy drugs during HIPEC, including carboplatin, doxorubicin and cisplatin. They can also utilize other chemotherapy drugs, based on the stage and type of the mesothelioma. In addition, they are able to alter the dosages of these medications to improve their effectiveness. During HIPEC the surgical team will be monitoring the patient's temperature and blood pressure to ensure that these vital body functions are not compromised.In HIPEC surgeons also utilize a cooling device to maintain the patient's temperature. This is crucial, since high temperatures can increase the toxic effects and side effects of certain chemotherapy drugs.As part of a multimodal approach, HIPEC has shown promising results for patients with mesothelioma. It can boost survival rates by a significant amount, especially in younger people with less invasive tumors. It also aids in treating malignant ascites, the build-up of fluid in the abdominal cavity that can be caused by various types of mesothelioma. However, it is an extremely invasive procedure that should only be performed in a university center with mesothelioma specialists who are experienced. Patients should be aware that this kind of treatment can take months to complete. During this time patients must take their time sleeping and follow the advice from their medical team to aid in healing and avoid complications. Patients should also exercise within their limits, and eat an appropriate diet to help their body heal.Therapy with a specific goalMesothelioma is a cancer that is found in the thin layer of tissue that covers the majority of your organs. It affects the lining of the chest and abdomen. Mesothelioma typically occurs in the pleura which is the lining around your lungs. However, it can be found in the peritoneum around your testicles or your heart. Exposure to asbestos fibers can cause mesothelioma decades before symptoms develop.The symptoms of peritoneal cancer include abdominal pain, swelling in the abdomen, weight loss, a buildup of fluid in the abdomen (ascites) and fatigue. The majority of patients experience these symptoms for a couple of months before their doctor determines that they have mesothelioma.There are a number of treatments for peritoneal mesothelioma, however targeted therapy is the most promising. This treatment targets the genetic mutations responsible for mesothelioma. These drugs are able to kill cancerous cells without harming healthy ones.Your doctor will determine whether you qualify for targeted treatment by examining biopsies or analyzing the results from other tests. They will then check whether your tumor has the molecular targets the drug is designed to target. This can be done using blood tests or a sample of your tumor, or computed (CT) scans.If doctors identify an area of interest, they will match it up with one of the targeted therapies. These drugs can kill cancer cells, stop them from growing, or instruct them to self-destruct. These drugs are available in the form of pills or delivered via intravenous drip.Targeted therapy is typically used in conjunction with other treatments such as surgery and radiation. In certain situations, it can be paired with immunotherapy agents such as Yervoy Opdivo and Tecentriq. These drugs can activate your immune system and help fight cancer.Your doctor will schedule regular visits to monitor your development. They will run blood and X-rays in order to evaluate your condition and see how well the targeted therapy is effective. They'll also inquire about how you're managing any side effects from the medication. The doctors will decide whether you should keep taking targeted therapy, or switch to a different medication.Therapy with radiationThe tissue that is a part of the lungs, called the pleura or the abdomen, the peritoneum is the most frequently encountered place where mesothelioma begins. The cancer begins to develop and spread once symptoms begin to show. The majority of patients were exposed to asbestos while at work.Mesothelioma usually occurs in later stages and is diagnosed when patients experience persistent symptoms that can be caused by other diseases or conditions. Mesothelioma treatment aims to manage the tumor while ensuring that symptoms are under control.Doctors use the peritoneal Cancer Index to determine the size of a patient's mesothelioma. The system divides the abdomen into 13 sections and assigns a number (0-3) according to the extent of tumor growth. Doctors then add the numbers to identify the mesothelioma stage. Stage 1 represents the least advanced mesothelioma. Stage 4 is the most advanced.Doctors also take into consideration the size and the extent of the primary tumor when determining if the peritoneal msothelioma has been identified. They also take into consideration whether the cancer has gotten to the lymph nodes as well as other organs, also known as metastasis.In general the greater the extent of mesothelioma a patient has is, the more difficult their outlook. However, there are many treatments available to improve the quality of life.The first step to the best mesothelioma outcome is finding an experienced mesothelioma specialist. The specialist can determine the most effective treatment for a patient's cancer stage and mesothelioma-cell type.Another option for treatment is targeted therapy, which makes use of drugs to kill cancer cells or stop them from growing and spreading. These medications can be taken in pill form or administered intravenously. The targeted therapy can be used alone or with other treatments.At UPMC doctors also provide a cutting-edge surgical technique called HIPEC. This procedure involves a surgeon taking out visible mesothelioma tumors in and around the abdominal cavity. Then the heated chemotherapy is in the abdomen. HIPEC is used to remove mesothelioma that is microscopic.The best treatment for mesothelioma is to begin immediately. A mesothelioma specialist can help those suffering from peritoneal cancer book an appointment.